Composition Glimepiride 2 mg +Metformin 500 mg S.R Tablets
Pack 10×10 Blister
MRP 1050


Glimepiride & Metformin Hydrochloride Prolonged Release Tablets – Glimepiride and metformin belong to a group of medicines called antidiabetics, which are used to treat type 2 diabetes, especially in patients whose blood sugar cannot be controlled with diet and exercise alone. Type 2 diabetes is a condition in which pancreas can’t make enough insulin to keep blood sugar levels within a healthy range. Gimepiride and Metformin Hydrochloride Prolonged Release Tablets is a combination of two diabetes drugs, glimepiride and metformin. Glimepiride works by stimulating insulin-producing beta cells in the pancreas. Thus, insulin helps in removing the sugar from blood. Metformin PR releases the drug in smaller doses over a longer period of time. Metformin reduces the production of sugar by liver cells and slows the absorption of sugar from the intestine. 

How Does Glimepiride & Metformin Hydrochloride Prolonged Tablet Work?

This medicine works by keeping blood sugar under control.

Glimepiride: Glimepiride is a sulfonylurea that lowers blood glucose by increasing the amount of insulin released by the pancreas.

Metformin: Metformin is a biguanide that reduces the production of glucose in the liver, slows the absorption of glucose from the intestine, and increases the body’s sensitivity to insulin.

Uses of Glimepiride & Metformin Hydrochloride Prolonged Tablets

Glimepiride and Metformin Hydrochloride Prolonged Release Tablets are commonly prescribed medications for managing type 2 diabetes. Here are their primary uses:

  1. Glimepiride: Glimepiride belongs to a class of drugs called sulfonylureas. It helps in lowering down the sugar in the blood by stimulating the pancreas to release more insulin, that would help the body to use glucose efficiently. This medication is primarily prescribed along with balanced-diet and exercise to control blood sugar level in people with type 2 diabetes.
  2. Metformin Hydrochloride: Metformin is a antibiotic drug that mitigates the amount of sugar production made by the liver and improves the body’s response to insulin. It also helps lower blood sugar by increasing glucose in muscle cells. Metformin is often considered the first-line treatment for type 2 diabetes and is often prescribed along with lifestyle changes such as diet and exercise.

When combined in an extended-release tablet, glimepiride and metformin hydrochloride work synergistically to regulate blood sugar throughout the day, providing more stable glucose levels and potentially reducing the risk of hypoglycemia (low blood sugar) associated with other diabetes medications. When taking these medications, it is important to follow your doctor’s instructions carefully and check your blood sugar levels regularly. 

Side Effects

  • Stomach pain
  • Nausea
  • Diarrhea
  • Vomiting
  • Headache
  • Metallic taste


  • Glimwpiride & Metformin tablet is not recommended for children.
  • Avoid breastfeeding while taking Glimepiride & Metformin as it may pass through the human milk.
  • Avoid alcohol consumption
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